17 February 2010
This has got to be one of the best studies I have ever seen - as a demonstration of how to waste time and money. As well, no doubt, as providing 'evidence' to frighten the less knowledgeable of the populace into cutting down on saturated animal fats to prevent obesity and osteoporosis (NOTE: Corn oil is not an animal fat and is not saturated - but I doubt that will stop someone using it as 'evidence' against them.)
I have never been a fan of extrapolating animal dietary studies to Homo sapiens. We have quite different reactions to foods. As you can read, these 'scientists' obviously share my views. But, after admitting that animal studies like this don't mimic human conditions, these 'scientists' conduct a trial on mice which, they say, serves as a model for humans!
Can anyone, please, tell me:
1. In what way does it have any relevance to anything other than, perhaps, female C57Bl/6J mice?
2. Do female C57Bl/6J mice even suffer from osteoporsis?
3. Should we care??
4. How on earth they get this cr*p published??
The abstract is below (I've got a PDF of the whole paper if anyone would like it)
Ganesh V. Halade, M. Rahman, Paul J. Williams and Gabriel Fernandes. High fat diet-induced animal model of age-associated obesity and osteoporosis.The Journal of Nutritional Biochemistry February 2010, [Article in Press, Corrected Proof]
Osteoporosis and obesity remain a major public health concern through its associated fragility and fractures. Several animal models for the study of osteoporotic bone loss, such as ovariectomy (OVX) and denervation, require unique surgical skills and expensive set up. The challenging aspect of these age-associated diseases is that no single animal model exactly mimics the progression of these human-specific chronic conditions. Accordingly, to develop a simple and novel model of post menopausal bone loss with obesity, we fed either a high fat diet containing 10% corn oil (CO) or standard rodent lab chow (LC) to 12-month-old female C57Bl/6J mice for 6 months. As a result, CO fed mice exhibited increased body weight, total body fat mass, abdominal fat mass and reduced bone mineral density (BMD) in different skeletal sites measured by dual energy X-ray absorptiometry. We also observed that decreased BMD with age in CO fed obese mice was accompanied by increased bone marrow adiposity, up-regulation of peroxisome proliferator-activated receptor γ, cathepsin k and increased proinflammatory cytokines (interleukin 6 and tumor necrosis factor α) in bone marrow and splenocytes, when compared to that of LC fed mice. Therefore, this appears to be a simple, novel and convenient age-associated model of post menopausal bone loss, in conjunction with obesity, which can be used in pre-clinical drug discovery to screen new therapeutic drugs or dietary interventions for the treatment of obesity and osteoporosis in the human population. (Emphasis added)
04 February 2010
When I wrote my first book, The Calorie Fallacy, in 1993, I included a chapter about the lack of weight loss benefit from such exercises as jogging. Apart from my Fluoride book, all of my books since then have included a chapter about the lack of evidence that exercising has much significant benefit to health. Even though I like to think of myself as an athlete, I recognise the difference between being 'fit' and being 'healthy'. Many people seem to think of the two words are synonymous, but they aren't. You can be fit enough to run a marathon, but drop dead of a heart attack walking to the start. The classic example is Jim Fixx, who started the jogging craze with his book, The Complete Book of Running, in 1977. He died of a heart attack while jogging!
Now, according to a study reported in the Daily Telegraph, the secret is out: "millions of people who strive to keep fit by jogging, swimming or going to the gym are wasting their time."
The article says: Researchers have discovered that the health benefits of aerobic exercise are determined by our genes - and can vary substantially between individuals.
Around 20 per cent of the population do not get any significant aerobic fitness benefit from regular exercise, according to an international study led by scientists at the University of London.
For these people, regular jogging and gym work will do little to ward off conditions like heart disease and diabetes which aerobic exercise is generally thought to resist.
Researchers say they would be better off abandoning their exercise regime and focusing on other ways of staying healthy - such as improving their diet or taking medication.
In the first chapter of Trick and Treat, I talked about how the ‘health industry’, and the pharmaceutical industry in particular, invented scares and ‘diseases’ so that they could capitalise on selling 'treatments' for those conditions.
The latest scam,‘The Swine Flu Pandemic’ scare, was one of the greatest medical scandals of the century, and was engineered to increase the profits of the drug companies, says the European Council's health chief, Dr Wolfgang Wodarg.
The council is to begin an investigation into the role of the drug companies, and how they influence ‘independent’ authorities such as the World Health Organization, after they passed a resolution from Wodarg, chairman of the Council’s health committee. Dr Wodarg, who is an epidemiologist and former health director in Germany, has followed the swine flu (H1N1 virus) pandemic story unfold. “It is one of the greatest health scandals of the century,” he says. “We have had a mild flu – and a false pandemic.”
The World Health Organization (WHO) declared the virus a pandemic last year, and health authorities around the world ordered in huge stocks of vaccines. The UK's chief medical officer, Sir Liam Donaldson, predicted 65,000 deaths in the UK, and convinced the government to place a £1bn order for swine flu vaccine. In the event, a mere 251 people in the UK have died from the virus, and the government is now desperately trying to offload vast stocks of the redundant vaccine.
Wodarg claims that governments have sealed contracts with drug companies that are triggered when a virus is classified as pandemic. “In this way the producers of vaccines are sure of enormous gains without having any financial risks. So they just wait until the WHO says ‘pandemic’ and activates the contracts.” As things stand with the contracts with the drugs companies, governments have no choice but to pay up.
And what do we do with all the unwanted, useless, vaccines? We give them to third-world countries - who are very unlikely to have a need for them!